Panton-Valentine toxin
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Panton-Valentine toxin
Panton-Valentine toxin. Computer artwork of the ribbon structure of a sub-unit of the Panton- Valentine leucocidin (PVL) toxin from the bacteria Staphylococcus aureus. This is the F sub-unit, it combines with as sub-unit to form the toxin. The toxin targets white blood cells, part of the bodys immune system. It makes pores in the white blood cells membrane, causing the cell contents to leak, and thus killing the cell. This destruction of cells leads to skin and soft tissue infections. These are mainly abscesses, but it can also cause pneumonia. The toxin has been found in strains of the antibiotic-resistant MRSA (methicillin-resistant S. Aureus) bacteria
Science Photo Library features Science and Medical images including photos and illustrations
Media ID 6279885
© DR MARK J. WINTER/SCIENCE PHOTO LIBRARY
Bacterial Ball And Stick Component Compound Dimer Methicillin Resistant Mrsa Pathogenic Pore Forming Ribbon Structure Staphylococcus Aureus Toxin Virulence Factor Bio Chemistry Biochemical Computer Artwork Micro Biology Microbiological Molecular Pathogen Protein
EDITORS COMMENTS
This computer artwork showcases the intricate ribbon structure of a sub-unit of the Panton-Valentine leucocidin (PVL) toxin, derived from the notorious Staphylococcus aureus bacteria. The featured sub-unit, known as F, collaborates with its counterpart to form this potent toxin. With white blood cells as its primary target, this malevolent substance disrupts the body's immune system by puncturing pores in their membranes. Consequently, these vital cells succumb to leakage and ultimately perish. The consequences of such cellular destruction manifest in various skin and soft tissue infections, predominantly abscesses but also potentially leading to pneumonia. Particularly alarming is that strains of methicillin-resistant S. aureus (MRSA), infamous for their antibiotic resistance capabilities, have been found to harbor this toxic compound. This mesmerizing illustration sheds light on the complex molecular architecture underlying pathogenicity and virulence factors within bacterial species. By delving into biochemistry and microbiology realms, scientists gain invaluable insights into understanding pathogens like S. aureus at a molecular level. Thanks to Science Photo Library's meticulous attention to detail in creating this stunning visual representation through advanced computer artistry techniques, we are provided an opportunity to appreciate both the beauty and danger inherent in these microscopic structures that shape our health landscape.
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