Nerve cell growth

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Nerve cell growth

Nerve cell growth. Fluorescent light micrograph of a PC12 cell following stimulation by nerve growth factor. The cell body contains the nucleus (green). The initially spherical cell has formed long branching extensions called neurites (yellow and pink). These neurites would form the axons and dendrons that connect nerve cells and transmit nerve impulses around the body, and the brain and spinal cord. PC12 cells are derived from a tumour of the adrenal gland (pheochromocytoma). Research into curing spinal paralysis uses nerve tissue cultures to investigate neural regeneration. Magnification: x980 when printed 10cm wide

Science Photo Library features Science and Medical images including photos and illustrations

Media ID 6421934

© DR TORSTEN WITTMANN/SCIENCE PHOTO LIBRARY

Actin Adrenal Gland Axon Axons Branched Branching C Ulture Connections Cultured Cytoskeleton Differentiating Differentiation Fluorescence Fluorescent Growing Growth Factor Immunofluorescence Immunofluorescent Microtubule Nerve Cell Nervous Net Work Neural Neurite Neurites Nucleus Paralysis Regeneration Spinal Stimulated System Treatment Tumour Light Micrograph Neurological Neurology

EDITORS COMMENTS
This print showcases the remarkable process of nerve cell growth. In this fluorescent light micrograph, a PC12 cell is depicted after being stimulated by nerve growth factor. The vibrant green nucleus resides within the cell body, which has undergone a fascinating transformation. Initially spherical in shape, the cell has now extended long branching extensions known as neurites, portrayed in shades of yellow and pink. These intricate neurites play a crucial role in forming axons and dendrons that connect nerve cells throughout the body, facilitating the transmission of vital nerve impulses. Derived from an adrenal gland tumor called pheochromocytoma, PC12 cells are instrumental in research aimed at finding treatments for spinal paralysis through neural regeneration. The image highlights the immense complexity of our nervous system's anatomy and its ability to intricately network itself. By magnifying this photograph 980 times when printed at 10cm wide, viewers can appreciate the fine details that contribute to our understanding of neurology and neurological disorders. Immunofluorescent staining techniques have enabled scientists to visualize specific components within these growing nerve cells such as actin filaments and microtubules that make up their cytoskeleton. This fluorescence allows us to witness firsthand how these cells differentiate and form connections with other neurons. Ultimately, this mesmerizing print captures both the beauty and scientific significance behind nerve cell growth—a visual testament to ongoing research efforts dedicated to unraveling one of nature's most complex systems: our own bodies' neural networks.

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