DNA and tumour suppressor complex C014 / 0014
Wall Art and Photo Gifts from Science Photo Library
DNA and tumour suppressor complex C014 / 0014
DNA and tumour suppressor complex. Molecular model showing a molecule of the p53 tumour suppressor protein (green, centre) bound to a damaged DNA (deoxyribonucleic acid) strand. p53 is an important checkpoint in the cell cycle, ensuring the integrity of DNA replication and thus supressing tumours and preventing cancers. Defects in p53 proteins, caused by defects in the TP53 gene that encodes them, are implicated in 50% of all cancers. Here such as defect has caused the DNA strand to be replicated poorly
Science Photo Library features Science and Medical images including photos and illustrations
Media ID 9202019
© LAGUNA DESIGN/SCIENCE PHOTO LIBRARY
Bound Cancer Cancerous Causing Cell Biology Cell Cycle Complex Complexed Compound Compounds Cytological Cytology Damage Damaged Dna Replication Genetic Oncological Oncology Preventing Prevention Proteins Proteomics Quaternary Structure Spacefill Spacefilled Suppression Tertiary Structure Tumor Abnormal Biochemical Biochemistry Cutouts Deoxyribonucleic Acid Genetics Integrity Molecular Model Protein Unhealthy
EDITORS COMMENTS
This print showcases the intricate molecular structure of a DNA and tumour suppressor complex. At the center of attention is the p53 tumour suppressor protein, depicted in vibrant green, bound to a damaged DNA strand. The p53 protein plays a crucial role as a checkpoint during the cell cycle, ensuring that DNA replication occurs accurately and effectively, thus preventing the formation of tumors and averting cancerous growth. However, defects in the TP53 gene responsible for encoding p53 proteins can lead to severe consequences. In fact, such defects are implicated in approximately 50% of all cancers. This particular illustration highlights how one such defect has resulted in poor replication of the DNA strand. The black background intensifies our focus on this fascinating biological phenomenon while emphasizing its significance within cellular biology and genetics. It serves as a reminder that maintaining the integrity and health of our genetic material is paramount for overall well-being. Through this visually striking artwork created by LAGUNA DESIGN/SCIENCE PHOTO LIBRARY, we gain insight into both the complexity and fragility underlying our genetic makeup. It prompts us to appreciate ongoing research efforts aimed at understanding these processes better while inspiring hope for advancements in cancer prevention and treatment through targeted therapies based on unraveling intricate molecular structures like this one.
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