Quaternary Structure Collection

Anaesthetic inhibiting an ion channel C015 / 6718
Anaesthetic inhibiting an ion channel. Computer model showing the structure of propofol anaesthetic drug molecules (spheres)

Tumour suppressor protein and DNA C017 / 3647
Tumour suppressor protein and DNA. Computer artwork showing a molecule of the tumour suppressor protein p53 (blue and pink) bound to a molecule of DNA (deoxyribonucleic acid, yellow and orange)

Ricin A-chain, artwork C017 / 3653
Ricin A-chain. Computer artwork showing the enzymatically active A-chain from a molecule of the toxic protein ricin. Ricin comprises two entwined amino acid chains; A (seen here) and B (not shown)

Ricin molecule, artwork C017 / 3652
Ricin molecule. Computer artwork showing the structure of a molecule of the toxic protein ricin. Ricin comprises two entwined amino acid chains; A (yellow) and B (blue)

Tumour suppressor protein and DNA C017 / 3644
Tumour suppressor protein and DNA. Computer artwork showing a molecule of the tumour suppressor protein p53 (blue and pink) bound to a molecule of DNA (deoxyribonucleic acid, yellow and orange)

Tumour suppressor protein and DNA C017 / 3646
Tumour suppressor protein and DNA. Computer artwork showing a molecule of the tumour suppressor protein p53 (blue and pink) bound to a molecule of DNA (deoxyribonucleic acid, yellow and orange)

HK97 bacteriophage procapsid. Molecular model showing the structure of the prohead-I procapsid of the HK97 bacteriophage. Bacteriophages are viruses that infect bacteria

Tumour suppressor protein and DNA C017 / 3645
Tumour suppressor protein and DNA. Computer artwork showing a molecule of the tumour suppressor protein p53 (blue and pink) bound to a molecule of DNA (deoxyribonucleic acid, yellow and orange)

Ricin A-chain, artwork C017 / 3654
Ricin A-chain. Computer artwork showing the enzymatically active A-chain from a molecule of the toxic protein ricin. Ricin comprises two entwined amino acid chains; A (seen here) and B (not shown)

Cyanobacterial circadian clock protein F006 / 9595
Cyanobacterial circadian clock protein, molecular model. This protein is a kinase known as KaiC. Its structure is a hexamer

DNA transcription, molecular model F006 / 9584
DNA transcription. Molecular model of the enzyme RNA polymerase II synthesising a mRNA (messenger ribonucleic acid) strand from a DNA (deoxyribonucleic acid) template

Yeast DNA recognition, molecular model F006 / 9282
Yeast DNA recognition. Computer model showing a GAL4 transcription activator protein bound to a yeast DNA (deoxyribonucleic acid) molecule (red and blue)

Sucrose-specific porin molecule F006 / 9218
Sucrose-specific porin, molecular model. Porins are proteins that span cell membranes and act as a channel through which specific molecules can diffuse

Bacterial ribosome and protein synthesis. Molecular model showing a bacterial ribosome reading an mRNA (messenger ribonucleic acid) strand (blue) and synthesising a protein

Tumour suppressor protein and DNA C017 / 3643
Tumour suppressor protein and DNA. Computer artwork showing a molecule of the tumour suppressor protein p53 (blue and pink) bound to a molecule of DNA (deoxyribonucleic acid, yellow and orange)

E. coli DNA mismatch repair complex. Computer model showing the structure of a MutS (Mutator S) protein from Escherichia coli (E)

Voltage-gated potassium channel. Computer model showing the molecular structure of a voltage-gated potassium (Kv) ion channel

Restriction enzyme cutting DNA
Fragment of DNA bound by the restriction endonucleaseEcoRI. The protein is a dimer, with each subunitable to bind and cut one strand of DNA

Packaged DNA molecule. Computer model showing the structure of a smoothly bent molecule of DNA (deoxyribonucleic acid) as it would appear in chromatin

MHC protein-antigen complex. Computer model showing a histocompatibility antigen complexed to a class II MHC (major histocompatibility complex) protein molecule

DNA mismatch repair complex. Computer model showing the structure of a MutS (Mutator S) protein binding to DNA (deoxyribonucleic acid) during DNA mismatch repair

Human electron transfer flavoprotein. Computer model showing the structure of a human electron transfer flavoprotein (ETF) molecule

Ribosomal RNA-binding protein molecule. Computer model showing the structure of a ribosomal protein L9 (RPL9) molecule from Bacillus stearothermophilus bacteria

Signal recognition particle RNA molecule. Computer model showing the molecular structure of the 2 A structure of helix 6 of the human signal recognition particle (SRP) RNA (ribonucleic acid)

Synthetic DNA triplex molecule. Computer model showing the molecular structure of a synthetic intramolecular DNA (deoxyribonucleic acid) triplex linked by hexakis(ethylene glycol) units

Ebola virus glycoprotein. Computer model showing the structure of a GP2 glycoprotein from the outer envelope of an Ebola virus (EBOV)

HP1 molecule C-terminal domain. Computer model showing the structure of the C terminal (shadow chromo) domain of a heterochromatin protein 1 (HP1) molecule from a mouse

Hepatitis D virus ribozyme complex. Computer model showing an RNA (ribonucleic acid) strand from an Hepatitis delta (Hepatitis D) virus genomic ribozyme, complexed with a ribonucleoprotein

Lumazine synthase molecule. Computer model showing the structure of a lumazine synthase enzyme molecule from a Brucella abortus bacterium

Poly(A)-binding protein and RNA complex. Computer model showing the structure of a poly(A)-binding protein (PABP) molecule bound to the poly(A)

Anaesthetic inhibiting an ion channel C015 / 6723
Anaesthetic inhibiting an ion channel. Computer model showing the structure of propofol anaesthetic drug molecules (spheres) bound to a pentameric ligand-gated ion channel (pLGIC, blue ribbons)

Anaesthetic inhibiting an ion channel C015 / 6722
Anaesthetic inhibiting an ion channel. Computer model showing the structure of propofol anaesthetic drug molecules (spheres) bound to a pentameric ligand-gated ion channel (pLGIC, blue ribbons)

Anaesthetic inhibiting an ion channel C015 / 6720
Anaesthetic inhibiting an ion channel. Computer model showing the structure of propofol anaesthetic drug molecules (lower left and right) bound to a pentameric ligand-gated ion channel (pLGIC, grey)

Anaesthetic inhibiting an ion channel C015 / 6721
Anaesthetic inhibiting an ion channel. Computer model showing the structure of propofol anaesthetic drug molecules (spheres)

Anaesthetic inhibiting an ion channel C015 / 6719
Anaesthetic inhibiting an ion channel. Computer model showing the structure of propofol anaesthetic drug molecules (spheres)

Myoglobin molecule C015 / 5164
Myoglobin molecule. Computer model showing the structure of a myoglobin molecule. Myoglobin is a protein found in muscle tissue

DNA and tumour suppressor complex C014 / 0014
DNA and tumour suppressor complex. Molecular model showing a molecule of the p53 tumour suppressor protein (green, centre) bound to a damaged DNA (deoxyribonucleic acid) strand

Canine parvovirus particle C013 / 9966
Canine parvovirus particle. Computer artwork showing the structure of the outer protein coat (capsid) of a canine parvovirus type 2 particle (virion)

Cholesteryl ester transfer protein C013 / 8895
Cholesteryl ester transfer protein molecule. Computer model showing the structure of a molecule of cholesteryl ester transfer protein (CETP)

Pit-1 transcription factor bound to DNA C013 / 8872
Pit-1 transcription factor bound to DNA. Molecular model showing pituitary-specific positive transcription factor 1 (Pit-1) (purple and yellow) bound to a strand of DNA (deoxyribonucleic acid)

Sucrose-specific porin molecule C013 / 8870
Sucrose-specific porin molecule. Moleuclar model showing the secondary and quaternary structure of a molecule of sucrose-specific porin

Glycated haemoglobin molecule C013 / 7781
Glycated haemoglobin molecule. Computer model of a glycated haemoglobin molecule. The alpha and beta subunits of the haemoglobin are blue and pink, and the iron-containing haem groups are grey

Glycated haemoglobin molecule C013 / 7779
Glycated haemoglobin molecule. Computer model showing a glucose molecule (centre) bound to a molecule of haemoglobin. The alpha and beta subunits of the haemoglobin are blue and pink

Glycated haemoglobin molecule C013 / 7780
Glycated haemoglobin molecule. Computer model showing a glucose molecule (centre) bound to a molecule of haemoglobin. The alpha and beta subunits of the haemoglobin are blue and pink

Haemoglobin molecule, artwork
Haemoglobin molecule. Computer artwork showing the molecular structure of haemoglobin, a metalloprotein that transports oxygen around the body in red blood cells

B-DNA molecule. Computer model showing the B structure of a DNA (deoxyribonucleic acid) molecule. DNA is composed of two strands twisted into a double helix

DNA crystal lattice. Computer model showing the crystal structure of a DNA (deoxyribonucleic acid) lattice. The lattice is built of small 3D triangular DNA subunits

Myoglobin molecule. Computer model showing the structure of a Myoglobin molecule. Myoglobin is a protein found in muscle tissue

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"Unveiling the Intricacies of Quaternary Structure: From Anaesthetic Inhibition to Tumour Suppression" The quaternary structure, a fascinating aspect of protein organization, plays a crucial role in various biological processes. One such example is seen with an anaesthetic inhibiting an ion channel (C015/6718), where the intricate arrangement of subunits determines its functionality. In the realm of cancer research, we delve into the interaction between tumour suppressor proteins and DNA (C017/3647). Understanding their quaternary structure sheds light on how these proteins regulate cell growth and prevent tumor formation. Similarly, exploring this relationship uncovers potential therapeutic targets for combating cancer. Artwork depicting Ricin A-chain (C017/3653) and Ricin molecule (C017/3652) showcases another intriguing facet of quaternary structure. These illustrations highlight how multiple subunits come together to form a deadly toxin or enzyme that can be harnessed for medical advancements. Continuing our exploration into tumour suppression mechanisms, we encounter further instances where tumour suppressor proteins interact with DNA (C017/3644 & C017/3646). The intricacies within their quaternary structures provide insights into genetic regulation and offer potential avenues for targeted therapies against malignancies. Moving beyond cancer-related studies, we encounter HK97 bacteriophage procapsid formations - examples that showcase viral capsids' complex assembly process. Investigating their quaternary structures allows us to understand viral infection mechanisms better while potentially identifying novel antiviral strategies. Rounding out our journey through diverse fields is artwork portraying Ricin A-chain (C017/3654), which emphasizes the importance of understanding protein architecture in designing countermeasures against biothreats like bioterrorism agents.