Enzyme catalysing DNA recombination
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Enzyme catalysing DNA recombination
Enzyme catalysing DNA recombination. Computer model of the enzyme flippase recombinase (FLP recombinase, atoms represented as tubes) mediating the recombination of strands of DNA (deoxyribonucleic acid, spacefill model) at a Holliday Junction. This recombination is a natural genetic process known as crossing over, and involves the exchanging of sections of DNA, between two different DNA strands. Recombinase enzymes snip open each DNA strand, forming a four-way alignment known as a Holliday Junction (at centre). This enzyme acts as both a ligase (bond-forming enzyme) and a lyase (bond-breaking enzyme)
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Media ID 6273739
© LAGUNA DESIGN/SCIENCE PHOTO LIBRARY
Atom Atoms Catalysing Combining Cross Over Crossing Over Enzyme Genetic Holliday Junction Mixing Molecules Nucleic Acid Proteomics Quaternary Recombination Rods Shape Space Fill Space Filled Structural Tetramer Tube Tubes Bio Chemistry Biochemical Deoxyribonucleic Acid Genetic Variation Genetics Molecular Molecular Model Protein
EDITORS COMMENTS
This print showcases a computer-generated model of the enzyme flippase recombinase, which plays a crucial role in catalysing DNA recombination. The intricate structure of this enzyme is represented by tubes, highlighting its complex nature and importance in genetic processes. At the heart of the image lies a Holliday Junction, where two different strands of DNA exchange sections through crossing over. Recombinase enzymes act as both bond-forming ligases and bond-breaking lyases, snipping open each DNA strand to create the four-way alignment observed at the center. This molecular dance enables genetic variation and contributes to biological diversity. The combination of biology and chemistry depicted here emphasizes how these disciplines intertwine to unravel the mysteries of life's building blocks. The atoms represented as tubes symbolize the structural intricacy that underlies biochemical reactions within our cells. This stunning artwork serves as a reminder that understanding DNA recombination is essential for comprehending fundamental aspects of genetics. It also highlights how scientific research continually unravels new insights into these microscopic processes. Science Photo Library presents this remarkable visual representation, showcasing not only their expertise but also their commitment to providing valuable resources for scientific exploration.
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