Dengue virus protein and antibody C016 / 2375
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Dengue virus protein and antibody C016 / 2375
Dengue virus protein and antibody. Molecular model of a dengue virus 2 envelope protein (yellow) complexed with antibody Mab 4E11 (purple). The function of the protein is to bind to the surface of its target cell and allow the viral genes into the cell, where replication occurs. Antibodies bind to the envelope proteins to prevent this. The dengue virus (DENV), transmitted by mosquito bites, causes the tropical disease dengue fever in humans. Symptoms can range from a mild fever and joint pain to spontaneous skin bleeding and death due to circulatory failure
Science Photo Library features Science and Medical images including photos and illustrations
Media ID 9202299
© LAGUNA DESIGN/SCIENCE PHOTO LIBRARY
Antibody Binding Biomolecule Bound Complex Complexed Graphic Haemorrhagic Immune System Immunological Immunology Macromolecule Microbiology Molecular Biology Molecules Proteins Proteomics Structural Viral Virology Biochemical Biochemistry Condition Cutouts Deoxyribonucleic Acid Disorder Hemorrhagic Microbiological Molecular Model Molecular Structure Protein
EDITORS COMMENTS
This print showcases the intricate molecular dance between the dengue virus protein and antibody C016/2375. The image depicts a molecular model of a dengue virus 2 envelope protein, colored in vibrant yellow, intricately intertwined with the purple antibody Mab 4E11. The envelope protein's crucial role is to bind to the surface of its target cell, enabling viral genes to enter and replicate within it. However, antibodies like Mab 4E11 play a vital defensive role by binding to these envelope proteins, preventing their interaction with host cells and thwarting viral replication. DENV, transmitted through mosquito bites, is responsible for causing dengue fever—a tropical disease that affects humans worldwide. The symptoms can range from mild fever and joint pain to severe manifestations such as spontaneous skin bleeding and circulatory failure leading to death. Set against a striking black background, this illustration highlights the complex nature of this disorder while emphasizing key elements such as structural complexity, biochemical interactions, and biological processes involved in both infection and immune response. This visually stunning artwork not only provides valuable insights into virology but also serves as a reminder of our ongoing battle against infectious diseases. It represents an amalgamation of biology, immunology, microbiology, biochemistry—showcasing how scientific research plays an essential role in understanding pathogens like DENV and developing effective strategies for prevention and treatment.
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