Action of serotonin reuptake inhibitors
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Action of serotonin reuptake inhibitors
Action of selective serotonin reuptake inhibitors (SSRIs) at a chemical synapse, computer artwork. Chemical synapses are the junctions between any two nerves (at right, blue) of the nervous system. SSRIs are a class of antidepressants used in the treatment of depression, anxiety disorders, and some personality disorders. They block the reuptake of serotonin to the presynaptic cell and therefore increase the extracellular level available to the postsynaptic cell downstream. Here serotonin is represented as white beads that have been blocked from reentering the presynaptic cell by the SSRI (red), at left. Serotonin is made in the frontal lobes of the brain and controls our moods
Science Photo Library features Science and Medical images including photos and illustrations
Media ID 6434147
© EQUINOX GRAPHICS/SCIENCE PHOTO LIBRARY
Action Antidepressant Anxiety Block Blocked Blocking Blocks Central Nervous System Drug Chemical Synapse Depression Diagram Drug Inhibit Inhibiting Inhibitor Nerve Nerves Neural Personality Pharmaceutic Pharmaceutical Pharmaceutical Treatment Pharmaceuticals Pharmacological Pharmacology Postsynaptic Presynaptic Preventing Psychology Serotonin Ssri Cells Condition Disorder Health Care Increases Inhibited Neurological Neurology
EDITORS COMMENTS
This computer artwork showcases the action of selective serotonin reuptake inhibitors (SSRIs) at a chemical synapse. In this illustration, we can observe the intricate junction between two nerves in the nervous system, represented by blue lines on the right side. SSRIs are a class of antidepressants widely used to treat various conditions such as depression, anxiety disorders, and some personality disorders. The main function of SSRIs is to block the reuptake of serotonin into the presynaptic cell, which ultimately leads to an increase in its extracellular level available for communication with downstream postsynaptic cells. The white beads symbolize serotonin molecules that have been successfully prevented from reentering the presynaptic cell by the red SSRI compound depicted on the left side. Serotonin plays a crucial role in regulating our moods and is produced in the frontal lobes of our brain. By inhibiting its reuptake, SSRIs help maintain higher levels of serotonin within neural pathways involved in mood regulation. This detailed illustration not only highlights how these pharmaceutical inhibitors work but also emphasizes their impact on mental health and neurological processes. It serves as a visual representation of how SSRIs act as powerful tools for increasing extracellular serotonin levels and providing relief for individuals suffering from depressive or anxious conditions.
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