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Artistic rendering of the surface of a human dendritic cell
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Artistic rendering of the surface of a human dendritic cell
Artistic rendering of the surface of a human dendritic cell illustrating the unexpected discovery of sheet-like processes that fold back onto the membrane surface. When exposed to HIV, these sheets entrap viruses in the vicinity and focus them to contact zones with T-cells targeted for infection. These studies were carried out using ion abrasion scanning electron microscopy, a new technology we have been developing and applying for 3D cellular imaging
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Media ID 13003089
© National Institutes of Health/Stocktrek Images
Analysis Bacteria Biology Biomedical Biotechnology Black Background Cell Cell Biology Cell Membrane Genetic Growth Healthcare Immune Cells Immune Response System Immune System Infection Infectious Disease Medical Medicine Membrane Microbiology Pathogen Research Rippled Surface Three Dimensional Virology Virus Wavy T Cells T Lymphocytes
EDITORS COMMENTS
This print showcases an artistic rendering of the surface of a human dendritic cell, shedding light on a groundbreaking discovery. The image reveals the unexpected presence of sheet-like processes that intricately fold back onto the membrane surface. What makes this finding even more remarkable is its relevance to HIV infection. When exposed to the virus, these sheets act as entrapment devices, capturing and concentrating viruses in close proximity to T-cells targeted for infection. This revelation was made possible through the application of ion abrasion scanning electron microscopy, an innovative technology developed by our team for three-dimensional cellular imaging. Against a striking black background, this horizontal color image captures the essence of medical research and biotechnology at its finest. It symbolizes progress in cell biology, microbiology, genetic analysis, and virology – all crucial fields contributing to our understanding of infectious diseases. Dendritic cells play a pivotal role in our immune response system's fight against pathogens like HIV. With their rippled and wavy cell membranes acting as gatekeepers against invading viruses, they serve as guardians protecting our body from harm. This extraordinary artwork represents not only scientific advancement but also serves as a reminder of how intricate and awe-inspiring life at a cellular level can be. Created by National Institutes of Health and brought to you by Stocktrek Images, it stands testament to humanity's relentless pursuit of knowledge in medicine and healthcare.
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