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TEM of T4 bacteriophage infecting E. coli

TEM of T4 bacteriophage infecting E. coli


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TEM of T4 bacteriophage infecting E. coli

Transmission electron micrograph of bacteriophage T4 (virus infecting bacteria), 60 minutes after the injection of its viral DNA into the bacterium Escherichia coli. The phage, specific to E.coli, is secured to the surface by means of spidery tail fibres. The tail, a contractile sheath, shortens to allow a syringelike tube (visible below base plate of tail) to penetrate the cell membrane, emptying the DNA contents of the head into the bacterium. The capsid, a protein coat surrounding the DNA, remains outside the cell. Synthesis & assembly of the phage within the cell follows rapidly. Mag: X220, 000 (at 10x8 size)

Science Photo Library features Science and Medical images including photos and illustrations

Media ID 6435165

© J. BROEK/BIOZENTRUM, UNIVERSITY OF BASEL SCIENCE PHOTO LIBRARY

Bacteriophage Bacteriophages Virology Viruses Micro Biology Virus


EDITORS COMMENTS
This print showcases the intricate process of a T4 bacteriophage infecting an Escherichia coli (E. coli) bacterium. Taken using transmission electron microscopy, the image reveals the moment 60 minutes after the injection of viral DNA into the E. coli cell. The T4 bacteriophage, specifically designed to target E. coli bacteria, is firmly attached to the bacterial surface through its spidery tail fibers. The tail features a contractile sheath that shortens, allowing a syringe-like tube to penetrate the cell membrane below its base plate. This tube acts as a conduit for emptying the DNA contents of the phage's head directly into the host bacterium. Interestingly, while most of its genetic material enters E. coli, leaving only its protein coat or capsid outside, this virus initiates rapid synthesis and assembly within its new host cell. This remarkable phenomenon demonstrates how viruses can hijack cellular machinery for their own replication and survival. With a magnification level of X220,000 at 10x8 size, this TEM image provides an extraordinary glimpse into one aspect of virology and microbiology research. It highlights not only nature's complexity but also scientists' ability to capture these microscopic events with incredible precision and detail. This photograph from Science Photo Library serves as a reminder that even in unseen realms like viruses and bacteria interactions lie fascinating stories waiting to be unraveled by scientific exploration.

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