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Immunofluorescent LM of an active macrophage
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Immunofluorescent LM of an active macrophage
Active macrophage. Immunofluorescent light micrograph of an active macrophage white blood cell producing the enzyme inducible nitric oxide synthetase (iNOS, red). The cytoplasm of the other as yet unactivated macrophages is dark green, while cell nuclei are blue. The enzyme iNOS converts the amino acid arginine into nitric oxide, an important signalling molecule that in this case is regulating and mediating the immune system. The macrophage has been activated by exposure to a mock bacterial infection. Macrophages help to kill invading organisms. Magnification: x200 at 5x7cm size
Science Photo Library features Science and Medical images including photos and illustrations
Media ID 6421244
© NANCY KEDERSHA/SCIENCE PHOTO LIBRARY
Active Cytoplasm Defence Enzyme Immune Immunofluores Immunology Infection Macrophage Macrophages System Cells Light Micrograph
EDITORS COMMENTS
This print from Science Photo Library showcases the intricate world of immunology within our own bodies. The image captures an active macrophage, a white blood cell responsible for defending against invading organisms. Through the use of immunofluorescent light microscopy, we can observe the enzyme inducible nitric oxide synthetase (iNOS) in vibrant red color within the cytoplasm of this activated macrophage. The dark green hue surrounding the active macrophage represents other as yet unactivated macrophages, highlighting their potential to join forces in combating threats to our immune system. Meanwhile, the blue nuclei serve as a reminder that these cells are at the core of our body's defense mechanism. In this particular case, exposure to a mock bacterial infection has triggered this specific macrophage's response and activation. The enzyme iNOS plays a crucial role by converting arginine into nitric oxide - an essential signaling molecule involved in regulating and mediating immune responses. At a magnification of x200 and printed at 5x7cm size, this print allows us to appreciate both the beauty and complexity found within our own anatomy. It serves as a powerful reminder of how our immune system works tirelessly behind-the-scenes to protect us from harm.
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