Creutzfeldt-Jakob diseased brain
Wall Art and Photo Gifts from Science Photo Library
Creutzfeldt-Jakob diseased brain
Creutzfeldt-Jakob disease (CJD). Computer artwork based on a light micrograph of a section through a human brain exhibiting CJD. Cell bodies of brain neurones (dark red) are surrounded by many white gaps or vacuoles. These are caused by the CJD prion, a virus-like protein. There are three types of CJD: the first appears, apparently without cause, in elderly people; the second affects those who have had transplants from infected people and the third, new variant CJD, is thought to be caused by eating cattle infected by the disease, bovine spongiform encephalopathy (BSE). The symptoms include dementia and myoclonus (sudden muscular contractions). Death occurs within two to three years
Science Photo Library features Science and Medical images including photos and illustrations
Media ID 6413666
© CHRISTIAN DARKIN/SCIENCE PHOTO LIBRARY
Bovine Human Brain Neurone Neurones Pathological Pathology Prion Vacuole Vacuoles Computer Artwork Condition Disorder
EDITORS COMMENTS
This print showcases the intricate details of a Creutzfeldt-Jakob diseased brain, shedding light on the devastating effects of this neurological disorder. Created through computer artwork based on a light micrograph, it vividly portrays the impact of CJD on brain tissue. The image reveals dark red cell bodies of brain neurones surrounded by numerous white gaps or vacuoles, which are caused by the CJD prion—a virus-like protein responsible for this debilitating disease. Three distinct types of CJD are depicted here: the first affecting elderly individuals seemingly without cause; the second afflicting those who have received transplants from infected donors; and finally, new variant CJD believed to stem from consuming cattle infected with bovine spongiform encephalopathy (BSE). CJD manifests in symptoms such as dementia and myoclonus—sudden muscular contractions—which ultimately lead to death within two to three years. This powerful visual representation serves as a reminder of the profound impact that neurodegenerative diseases can have on human lives. Through its combination of biology, medicine, and pathology, this illustration provides valuable insights into both the biological mechanisms underlying CJD and its pathological consequences within the human brain. It stands as a testament to ongoing scientific research aimed at understanding and combating these complex disorders that continue to challenge medical professionals worldwide.
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