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Blood coagulation cascade, artwork C016 / 9873

Blood coagulation cascade, artwork C016  /  9873


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Blood coagulation cascade, artwork C016 / 9873

Blood coagulation cascade. Artwork of the biochemical cascade of blood chemicals and proteins during blood clotting (coagulation). The blood vessel and its layered wall is at upper left. The main diagram shows a clot forming at the damaged area (upper right). This occurs via reaction chains known as pathways mediated by factor X proteins (red spheres). The extrinsic pathway (down centre, blue arrows) and intrinsic pathway (down left, yellow arrows) unite in the common pathway (up right, from thrombin, yellow sphere) to form the blood clot. This consists of fibrin (yellow trefoils), platelets (pink puzzle pieces), red blood cells (red discs), and white blood cells (light blue spheres)

Science Photo Library features Science and Medical images including photos and illustrations

Media ID 9232799

© JOSE ANTONIO PE

Bleeding Cascade Cascades Chemicals Clot Clotting Coagulating Cofactor Collagen Erythrocyte Erythrocytes Fibrin Fibrinogen Haematological Haematology Healing Leucocyte Leucocytes Pathways Phospholipid Phospholipids Physiological Physiology Platelet Platelets Polymerisation Polymerization Process Processes Proteins Reacting Reaction Red Blood Cell Schematic Thrombin Vascular White Blood Cell Wound Artery Biochemistry Blood Vessel Cells Circulation Circulatory System Fvii Fviia Fviii Fxii Protein Stabilisation


EDITORS COMMENTS
This print titled "Blood Coagulation Cascade" showcases the intricate biochemical process that occurs during blood clotting. The artwork, created by JOSE ANTONIO PEÑAS, provides a detailed illustration of the cascade of blood chemicals and proteins involved in this essential physiological function. In the upper left corner, we see a blood vessel with its layered wall, emphasizing the vascular context in which coagulation takes place. Moving towards the upper right, the main diagram reveals a clot forming at a damaged area. This clot formation is facilitated by factor X proteins represented as red spheres, mediating reaction chains known as pathways. The blue arrows represent the extrinsic pathway while yellow arrows depict the intrinsic pathway. These two pathways converge into what is known as the common pathway located in the upper right section of the image. Thrombin (depicted as a yellow sphere) plays a crucial role in this stage and contributes to fibrin formation (yellow trefoils), along with platelets (pink puzzle pieces), red blood cells (red discs), and white blood cells (light blue spheres). Overall, this artwork beautifully captures both scientific accuracy and artistic expression. It serves as an educational tool for understanding not only how our bodies respond to wounds or cuts but also highlights key components such as various proteins, chemicals, and cellular elements involved in this complex healing process.

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