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Atorvastatin cholesterol-lowering drug

Atorvastatin cholesterol-lowering drug


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Atorvastatin cholesterol-lowering drug

Atorvastatin cholesterol-lowering drug, molecular model. Atorvastatin, marketed by Pfizer as Lipitor, was the best-selling drug in the world in 2004. It inhibits an enzyme responsible for the production of cholesterol in the liver, thus reducing the amount of cholesterol in the blood. As cholesterol production slows, liver cells take up low density lipoprotein (LDL) cholesterol from the blood. High blood levels of LDL (often called " bad" ) cholesterol lead to atherosclerosis, causing increased blood pressure and heart disease. This is one of the biggest killers in the developed world. Atoms are colour-coded: carbon (blue), oxygen (orange), nitrogen (purple), fluorine (green) and hydrogen (white)

Science Photo Library features Science and Medical images including photos and illustrations

Media ID 6280617

© DR TIM EVANS/SCIENCE PHOTO LIBRARY

Cardiovascular Disease Cholesterol Cholesterol Lowering Compound Compounds Drug Pfizer Pharmaceutical Pharmaceutics Pharmacological Pharmacology Spheres Statin Statins Bio Chemistry Biochemical Computer Artwork Health Care Molecular Molecular Model


EDITORS COMMENTS
This print showcases the molecular model of Atorvastatin, a powerful cholesterol-lowering drug that revolutionized the pharmaceutical industry. Developed by Pfizer and marketed as Lipitor, this groundbreaking medication held the title of being the best-selling drug worldwide in 2004. The intricate molecular structure depicted in vibrant colors represents how Atorvastatin inhibits an enzyme responsible for cholesterol production in the liver. By doing so, it effectively reduces cholesterol levels in the bloodstream. As a result, liver cells actively absorb low-density lipoprotein (LDL) cholesterol from the blood. High levels of LDL cholesterol are often referred to as "bad" because they contribute to atherosclerosis - a condition that leads to increased blood pressure and heart disease. In fact, cardiovascular diseases caused by excessive LDL cholesterol remain one of the leading causes of death in developed countries. This visually striking image serves as a reminder of both scientific progress and medical advancements aimed at combating these life-threatening conditions. The spheres representing different atoms - carbon, oxygen, nitrogen, fluorine, and hydrogen - highlight how each element plays a crucial role within this complex compound. As we delve into biochemistry and pharmacology through this mesmerizing artwork, we gain insight into how innovative drugs like Atorvastatin continue to transform healthcare practices while offering hope for millions around the world seeking improved cardiovascular health.

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