Electron Cryomicroscopy Collection

Cucumber necrosis virus, computer model
Cucumber necrosis virus (CNV), computer model. This image was created using molecular modelling software and data from cryo-electron microscopy

Human rhinovirus, computer model
Human rhinovirus (HRV) with intercellular adhesion molecule 1 (ICAM-1), computer model. This image was created using UCSF Chimera molecular modelling software and data from cryo-electron microscopy

Ribgrass mosaic virus, computer model
Ribgrass mosaic virus (RMV), computer model. This image was created using UCSF Chimera molecular modelling software and fibre X-ray diffraction

Human rhinovirus with antibodies
Human rhinovirus (HRV) with antibody fragments, computer model. This image was created using molecular modelling software and data from cryo- electron microscopy

Bacteriophage phi29, computer model
Bacteriophage phi29. Cross section computer model of phi29 created using UCSF Chimera molecular modelling software and data from cryo-electron microscopy

Simian immunodeficiency virus (SIV), computer model. Cross section of SIV created using 3-D molecular modelling software and data from cryo- electron microscopy

Sindbis virus, computer model
Sindbis virus. Computer model of sindbis virus created using UCSF Chimera molecular modelling software and data from cryo-electron microscopy. It shows the outer glycoprotein shell of the virus

Semliki Forest virus, computer model
Semliki Forest virus (SFV), computer model. This image was created using UCSF Chimera molecular modelling software and data from cryo-electron microscopy

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Electron cryomicroscopy (cryo-EM) has revolutionized the field of structural biology, allowing scientists to visualize intricate details of various viruses and their interactions with antibodies. Using this cutting-edge technique, researchers have captured stunning images of Bacteriophage phi29, Simian immunodeficiency virus (SIV), Cucumber necrosis virus, Human rhinovirus, and Ribgrass mosaic virus. These high-resolution computer models provide invaluable insights into the architecture and behavior of these viral entities. In one captivating image, a computer model showcases Bacteriophage phi29 in all its glory. This bacteriophage is known for its unique shape and ability to infect bacteria efficiently. The cryo-EM visualization allows us to appreciate the intricate structure that enables this tiny organism's remarkable functionality. Moving on to another fascinating subject, we delve into the realm of virology by exploring Simian immunodeficiency virus (SIV). Cryo-EM reveals the complex arrangement of proteins that make up SIV's outer shell. Understanding such structures aids in developing targeted therapies against similar viruses like HIV. The exploration continues as we encounter Cucumber necrosis virus through a detailed computer model generated using electron cryomicroscopy techniques. By deciphering its structure at an atomic level resolution, scientists gain crucial knowledge about how this plant pathogen operates within cucumber plants. Shifting our focus back to human health concerns, we investigate Human rhinovirus - one of the main culprits behind common colds. Through advanced imaging methods like cryo-EM combined with computational modeling approaches, researchers can study different strains and develop potential antiviral strategies. Additionally, electron cryomicroscopy provides us with a glimpse into how antibodies interact with Human rhinovirus particles. This visual representation helps elucidate mechanisms by which our immune system neutralizes viral threats effectively. Returning once again to bacteriophages – viruses that infect bacteria – we explore Bacteriophage P22.