Images Dated 14th December 2004

Dog - Continental Toy Spaniel: Papillon

LA-2350 Dog - Continental Toy Spaniel: Papillon. In the USA the Papillon is not distinguished from the Phalene Jean Michel Labat Please note that prints are for personal display purposes only and may not be reproduced in any way

© J. M. Labat / ardea.com

Breed, Companion Breeds, Dog, Domestic, Ear, Feet, Ground Level, Inside, Mammal, Odd Angle, Papillon, Paw, Pet, Quirky, Single, Stdio, Toy Breeds

Great Northern Hotel

The facade of the Great Northern Hotel at King's Cross, London, opened in 1854. Pictured circa 1890. (Photo by London Stereoscopic Company/Hulton Archive/Getty Images)

© 2004 Getty Images

1 1, 109, 13912, 15635, 51858326, Architecture, Box, Company, Cross, Diry, England, Europe, Format, Hotel, J90373701, Landscape, London, Stereoscopic, T Bri London Kings

Immunofluorescent LM of an active macrophage

Active macrophage. Immunofluorescent light micrograph of an active macrophage white blood cell producing the enzyme inducible nitric oxide synthetase (iNOS, red). The cytoplasm of the other as yet unactivated macrophages is dark green, while cell nuclei are blue. The enzyme iNOS converts the amino acid arginine into nitric oxide, an important signalling molecule that in this case is regulating and mediating the immune system. The macrophage has been activated by exposure to a mock bacterial infection. Macrophages help to kill invading organisms. Magnification: x200 at 5x7cm size

© NANCY KEDERSHA/SCIENCE PHOTO LIBRARY