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TEM of Leishmania sp
False-colour transmission electron micrograph (TEM) of Leishmania sp., a parasitic flagellate protozoan that causes the disease leishmaniasis in humans. The parasite assumes a different form in each of its two hosts, humans & the sandfly, its insect carrier. This example, from human tissue, appears as an elongated oval structure, with no protruding flagellum, and is known as a Leishman- Donovan body. Here, the flagellum (outlined in pink) appears retracted. In its sandfly host, it takes on an elongated, motile (flagellate) form. Human infection affects cells of the lymphatic system, spleen & bone marrow. Magnification: x7, 600 at 6x7cm, x3, 800 at 35mm size
© CNRI/SCIENCE PHOTO LIBRARY